Module I – Scientific Foundation
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Module Contribution (22% – 33 Questions)
Knowledge Areas
- Advanced Pathophysiology Understand CNS disease mechanisms, neuroendocrine links, and inflammation in psychiatric disorders.
- Advanced Pharmacology Know contraindications (e.g., MAOIs + SSRIs), drug interactions (CYP450), and adverse effects (e.g., QT prolongation, metabolic syndrome).
- Advanced Psychopharmacology Master pharmacokinetics (ADME), pharmacodynamics (receptor targets), and emergency recognition of EPS and NMS (FEVER mnemonic).
- Neurodevelopment Focus on brain maturation, synaptic pruning, and disorders like ADHD and autism.
- Neuroanatomy Key regions: frontal (executive), limbic (emotion), basal ganglia (movement), hippocampus (memory).
- Neurophysiology Understand neuron signaling, neurotransmitters (dopamine, serotonin, GABA, glutamate), and synaptic transmission.
- Psychogenomics Know gene-drug interactions (e.g., CYP2D6 variants), heritability of psychiatric conditions, and pharmacogenetic testing.
- Advanced Physical Assessment Perform focused neuro exams, assess cognition and affect, and use tools like MMSE and MoCA for screening.
Clinical Tip for PMHNPs:
- SSRIs are metabolized by CYP2D6 and CYP3A4—watch for interactions.
- Lithium is excreted renally—monitor kidney function closely.
- Lipophilic drugs (e.g., benzodiazepines) cross the blood-brain barrier more easily.
- Course Management
- Communication and Collaboration
- User-Friendly Interface
- Educational Institutions
- Businesses and Organization
- Individual Learners
- User-Friendly Interface
- Robust Course Management Capabilities
- Effective Communication and Collaboration

Dr. Davina Uchegbu, DNP, PMHNP-BC, MSN-NL Dr. Davina Uchegbu is a board-certified Psychiatric-Mental Health Nurse Practitioner with a Doctor of Nursing Practice and a Master of Science in Nursing Leadership. She brings a unique blend of clinical expertise and strategic leadership to the field of mental health, delivering compassionate, evidence-based care while advancing systems that support patient outcomes and provider excellence. With a strong foundation in psychiatric diagnostics, psychopharmacology, and therapeutic interventions, Dr. Uchegbu is committed to holistic, culturally responsive care. Her leadership background informs her work in program development, team coordination, and quality improvement—making her a dynamic force in both clinical and administrative settings. Dr. Uchegbu is also an advocate for mental health education and professional mentorship, empowering future clinicians with the tools, confidence, and clarity to thrive in practice.With a DNP and a master’s in nursing leadership, she understands both the clinical and organizational sides of healthcare—and she’s here to share that insight with you. Whether she’s teaching psychiatric care, precepting nurse Practitioners, or mentoring new providers through change, Dr. Uchegbu leads with empathy, clarity, and purpose. Her goal is to help you not only succeed in your studies, but thrive in your career. She provides compassionate, evidence-based mental health care and leads initiatives that improve clinical outcomes and team performance. With a dual focus on patient wellness and professional development, Dr. Uchegbu is a trusted voice in psychiatric care and nursing mentorship.
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